ISO 17099:2014解决了以下问题: a）客户和实验室的个人信息保密; b）实验室安全要求; c）用于建立校准参考剂量效应曲线的辐射源，剂量率和范围，允许来自CBMN测定产量的剂量估计和最小可分辨剂量; d）CBMN分析评分采集，培养，收获和样品制备的性能; e）评分标准; f）将双核细胞中的微核频率转换为吸收剂量的估计值; g）结果报告; h）质量保证和质量控制; i）包含问卷调查示例，客户说明，显微镜评分数据表，示例报告和关于自动化微核评分的当前自动化系统的优点和局限性的建议的附录

ISO 17099:2014 addresses the following: a) confidentiality of personal information for the customer and the laboratory; b) laboratory safety requirements; c) radiation sources, dose rates, and ranges used for establishing the calibration reference dose-effect curves allowing the dose estimation from CBMN assay yields and the minimum resolvable dose; d) performance of blood collection, culturing, harvesting, and sample preparation for CBMN assay scoring; e) scoring criteria; f) conversion of micronucleus frequency in binucleated cells into an estimate of absorbed dose; g) reporting of results; h) quality assurance and quality control; i) informative annexes containing examples of a questionnaire, instructions for customers, a microscope scoring data sheet, a sample report and advice on strengths and limitations of current automated systems for automated micronucleus scoring.