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Radiological protection. Performance criteria for laboratories using the cytokinesis block micronucleus (CBMN) assay in peripheral blood lymphocytes for biological dosimetry 辐射防护 用于生物剂量测定的外周血淋巴细胞胞质分裂阻滞微核(CBMN)试验实验室的性能标准
发布日期: 2018-01-31
BS EN ISO 17099:2017解决了以下问题:a)客户和实验室个人信息的保密性;b) 实验室安全要求;c) 用于确定校准参考剂量效应的辐射源、剂量率和范围 允许根据CBMN分析产量和最小可分辨剂量估算剂量的曲线;d) 为CBMN分析评分进行血液采集、培养、采集和样品制备;e) 评分标准;f) 将双核细胞的微核频率转换为吸收剂量的估计值;g) 报告结果; h) 质量保证和质量控制;i) 包含问卷示例、客户说明、 显微镜评分数据表、样本报告以及关于当前技术优势和局限性的建议 用于自动微核评分的自动化系统。购买本文件时可获得的所有当前修订均包含在购买本文件中。
BS EN ISO 17099:2017 addresses the following:a) confidentiality of personal information for the customer and the laboratory;b) laboratory safety requirements;c) radiation sources, dose rates, and ranges used for establishing the calibration reference dose-effect curves allowing the dose estimation from CBMN assay yields and the minimum resolvable dose;d) performance of blood collection, culturing, harvesting, and sample preparation for CBMN assay scoring;e) scoring criteria;f) conversion of micronucleus frequency in binucleated cells into an estimate of absorbed dose;g) reporting of results;h) quality assurance and quality control;i) informative annexes containing examples of a questionnaire, instructions for customers, a microscope scoring data sheet, a sample report and advice on strengths and limitations of current automated systems for automated micronucleus scoring.All current amendments available at time of purchase are included with the purchase of this document.
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发布单位或类别: 英国-英国标准学会
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