进行了一项研究，以评估在用二氧化氯消毒时，MS 2噬菌体和枯草芽孢杆菌孢子作为贾第虫和隐孢子虫灭活的微生物指标的使用情况。微生物加标实验是在实验室规模的间歇系统中进行的。研究了水基质、温度、接触时间、二氧化氯剂量和过滤压力（通过实验室规模的砂剪切程序模拟）等因素，以评估它们对微生物失活的影响。结果表明，枯草芽孢杆菌孢子可能是隐孢子虫卵囊失活的一种可行的微生物指示剂。此外，剪切应力似乎在20℃时促进微生物失活？C.因此，当应用该方法计算在后过滤器位置添加二氧化氯导致的微生物失活时，公布的CxT值可能包含一个额外的安全系数。

A study was performed to evaluate the use of MS 2 phages and Bacillus subtilis spores as microbial indicators for Giardia and Cryptosporidium inactivation when disinfecting with chlorine dioxide. Microbial spiking experiments were performed at bench-scale in batch systems. Factors such as water matrix, temperature, contact time, chlorine dioxide dose and filtration stress (as simulated by a bench-scale sand shearing procedure) were examined to assess their impact on microbial inactivation. Results indicate that Bacillus subtilis spores may be a feasible microbial indicator for the inactivation of Cryptosporidium oocysts. Furthermore, shearing stress appears to promote microbial inactivation at 20?C. Consequently, published CxT values may have an additional safety factor included in them when this approach is applied to calculate microbial inactivation resulting from the addition of chlorine dioxide at a post-filter location.