Cosmetics — Analytical methods — Nitrosamines: Detection and determination of N-nitrosodiethanolamine (NDELA) in cosmetics by HPLC, post-column photolysis and derivatization
化妆品和化妆品;分析方法——亚硝胺:通过HPLC、柱后光解和衍生化检测和测定化妆品中的N-亚硝二乙醇胺(NDELA)
发布日期:
2009-12-03
ISO 10130:2009描述了一种检测和定量N?通过高效液相色谱(HPLC)结合柱后光解和衍生化对化妆品和化妆品中的亚硝基二乙醇胺(NDELA)进行了分析。
该方法不适用于NDELA以外的亚硝胺的检测和/或定量,也不适用于化妆品或化妆品中使用的原料以外的产品中的NDELA的检测和/或定量。
如果产品有可能受到成分的NDELA污染或成分的组成形成NDELA,则该方法将用于化妆品的测试,并且是ISO 15819的替代方法。
该方法不适用于含有氧化染料的基质。
ISO 10130:2009 describes a method for the detection and quantification of N?nitrosodiethanolamine (NDELA) in cosmetics and raw materials used in cosmetics by High Performance Liquid Chromatography (HPLC) coupled with post-column photolysis and derivatization.
This method is not applicable to the detection and/or quantification of nitrosamines other than NDELA, nor to the detection and/or quantification of NDELA in products other than cosmetics or raw materials used in cosmetics.
If a product has the possibility of either NDELA contamination from the ingredients or NDELA formation by the composition of ingredients, the method will be applied for the testing of cosmetic products and is an alternative to ISO 15819.
This method is not applicable to matrices containing oxidation dyes.