进行了研究，以探讨一氯胺反应可产生N-亚硝二甲胺（NDMA）的假设。二甲胺（DMA）被用作潜在的前体。NDMA是由DMA和一氯胺反应生成的。NDMA的形成随着一氯胺浓度的增加而增加。爱荷华河水中未形成大量NDMA。然而，向爱荷华州河水中添加0.5 mM和1.0 mM的一氯胺，分别产生5.6 ng/L和14.1 ng/L。由DMA和15N同位素标记的一氯胺15NH2Cl形成的NDMA的质谱表明，NDMA中硝基氮的来源是一氯胺。因此，NDMA可能是一种“新”的消毒方法- 产物形成的机理可能不涉及N-亚硝化途径。提出了在氨存在下氯胺化或氯化过程中生成NDMA的反应机理。包括14篇参考文献。

Studies were conducted to investigate the hypothesis that N-nitrosodimethylamine (NDMA) can be produced from the reaction involving monochloramine. Dimethylamine (DMA) was used as a potential precursor. NDMA was formed from the reaction between DMA and monochloramine. The formation of NDMA increased with increased monochloramine concentration. No significant amount of NDMA was formed in Iowa River water. However, addition of 0.5 mM and 1.0 mM of monochloramine to Iowa River water produced 5.6 ng/L and 14.1 ng/L, respectively. The mass spectra of the NDMA formed from DMA and 15 N isotope labeled monochloramine, 15 NH2Cl, showed that the source of the nitro group nitrogen in NDMA was from monochloramine. NDMA, therefore, could possibly be a "new" disinfection by-product formed in mechanism that may not involve N-nitrosation pathway. The reaction mechanism of NDMA formation during chloramination or chlorination in the presence of ammonia was proposed. Includes 14 references.