ISO 10253:2016规定了一种测定海水中含有的物质和混合物或环境水样（流出物、洗脱物等）对单细胞海藻Skeletonema sp.和Phaeodactylum tricornutum生长抑制的方法。 该方法可用于测试易溶于水且不会以任何其他方式从测试介质中显著降解或消除的物质。

ISO 10253:2016 specifies a method for the determination of the inhibition of growth of the unicellular marine algae Skeletonema sp. and Phaeodactylum tricornutum by substances and mixtures contained in sea water or by environmental water samples (effluents, elutriates, etc.). The method can be used for testing substances that are readily soluble in water and are not significantly degraded or eliminated in any other way from the test medium.