This paper presents some of the latest developments in disinfection technology with the intent of advancing the knowledge and application of disinfection in the potable water industry. This is of significance to the industry since the use of inappropriate design relationships can lead to incorrectly sized and operated disinfection processes leading to inappropriate disinfection, unnecessary disinfection byproducts, and inefficient use of resources. The research described here builds on the Integrated Disinfection Design Framework (IDDF) project. This follow-on project was intended to develop protocols that could take the framework from a theoretical exercise to implementation at an operating utility. We describe in this paper the protocols that have been developed for implementation of the IDDF at three utilities. The principal objectives of this paper are: to provide basic information on the development of input parameters to the IDDF; to describe the integrated disinfection design framework (IDDF); and, to describe implementation protocols for the IDDF.