这项研究由美国环保署饮用水研究部（DWRD）进行，研究了三个采用俄亥俄河水常规处理的平行试验工厂中副产品的形成和控制。在一家工厂，过滤后使用氯气，允许进行常规处理以去除前体材料。在第二家工厂，过滤后也使用了氯，但在原水中使用了臭氧，以加强前体控制。在第三家工厂，一氯胺被用于过滤水，臭氧被用于原水。

This study, which was conducted by EPA's Drinking Water Research Division (DWRD), examined byproduct formation and control in three parallel pilot plants employing conventional treatment of Ohio River water. In one plant, chlorine was applied following filtration, allowing conventional treatment to remove precursor materials. In a second plant, chlorine was also applied following filtration, but ozone was applied to the raw water to enhance precursor control. In a third plant, monochloramine was applied to filtered water with ozone applied to raw water.