Membrane replacement requires careful planning, and should involve computermodeling, membrane probing, membrane profiling and hydraulic evaluations todocument modifications in plant performance. Although many existing plants haveundergone membrane replacement, little information has been published in theliterature on this component of membrane plant operation. The purpose of thispaper is to present an overview of membrane replacement, and describe two casestudies to document membrane replacement. One case study describes membranereplacement at a hollow fiber membrane facility (Sarasota, Florida), and a secondcase study describes membrane replacement at a spiral-wound membrane facility(Marco Island, Florida). Includes tables, figure.